Frank Tacke Selected Research

Cytokines

3/2023	Serum CXCL5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression.
1/2023	Cholangiokines: undervalued modulators in the hepatic microenvironment.
10/2022	Inflammatory Cytokines Associated with Diagnosis, Tumor Grade and Prognosis in Patients with Neuroendocrine Tumors.
1/2021	Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction.
8/2020	The NLRP3 Inflammasome in Alcoholic and Nonalcoholic Steatohepatitis.
1/2020	Controversies and Opportunities in the Use of Inflammatory Markers for Diagnosis or Risk Prediction in Fatty Liver Disease.
12/2019	Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients.
6/2019	Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients.
1/2019	Polypropylene mesh implantation for hernia repair causes myeloid cell-driven persistent inflammation.
6/2018	IL-6 and IL-8 Serum Levels Predict Tumor Response and Overall Survival after TACE for Primary and Secondary Hepatic Malignancies.

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Frank Tacke Research Topics

Disease

118	Inflammation (Inflammations) 05/2024 - 06/2003
107	Fibrosis (Cirrhosis) 05/2024 - 04/2002
95	Liver Cirrhosis (Hepatic Cirrhosis) 02/2024 - 06/2002
75	Neoplasms (Cancer) 01/2024 - 05/2010
65	Liver Diseases (Liver Disease) 11/2023 - 04/2002
57	Critical Illness (Critically Ill) 02/2024 - 08/2008
50	Sepsis (Septicemia) 02/2024 - 08/2008
40	Non-alcoholic Fatty Liver Disease 02/2024 - 01/2014
40	Infections 06/2023 - 04/2002
37	Hepatocellular Carcinoma (Hepatoma) 06/2024 - 04/2003
18	Fatty Liver 01/2024 - 05/2005
17	Obesity 03/2024 - 01/2009
16	COVID-19 04/2024 - 01/2020
16	Hepatitis 04/2023 - 04/2002
15	Disease Progression 01/2024 - 08/2007
15	Liver Neoplasms (Liver Cancer) 01/2023 - 05/2010
13	Insulin Resistance 01/2023 - 05/2005
12	Hemorrhage 09/2023 - 04/2003
11	Hepatitis B 12/2023 - 04/2002
11	Neoplasm Metastasis (Metastasis) 11/2023 - 04/2016
11	Alcoholic Fatty Liver 01/2023 - 03/2012
10	Acute Liver Failure (Fulminant Hepatic Failure) 01/2024 - 04/2008
9	Hepatitis C 01/2022 - 01/2010
8	Renal Insufficiency (Renal Failure) 12/2023 - 01/2009
8	End Stage Liver Disease 04/2023 - 06/2006
8	Necrosis 01/2023 - 12/2011
8	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2023 - 06/2019
7	Portal Hypertension 05/2024 - 07/2003
7	Sclerosing Cholangitis 12/2023 - 01/2017
6	Cholangiocarcinoma 01/2023 - 01/2016
6	Type 2 Diabetes Mellitus (MODY) 12/2022 - 01/2009
6	Colitis 07/2018 - 09/2008
5	Brain Death (Brain Dead) 02/2024 - 01/2016
5	Carcinogenesis 01/2024 - 10/2013
5	Hypoxia (Hypoxemia) 12/2023 - 12/2014
5	Cholestasis 12/2023 - 05/2005
5	Cicatrix (Scar) 01/2023 - 10/2012
5	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2022 - 01/2011
5	Atherosclerosis 10/2021 - 03/2006
5	Chronic Hepatitis B 01/2021 - 08/2004
4	Short Bowel Syndrome 09/2023 - 01/2021

Drug/Important Bio-Agent (IBA)

83	Biomarkers (Surrogate Marker)IBA 04/2024 - 07/2003
39	CytokinesIBA 03/2023 - 09/2008
34	ChemokinesIBA 12/2023 - 11/2006
27	Chemokine ReceptorsIBA 04/2023 - 03/2006
24	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2007
22	LigandsIBA 11/2023 - 08/2007
19	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2011
16	Urokinase Plasminogen Activator ReceptorsIBA 05/2024 - 01/2011
16	Antiviral Agents (Antivirals)IBA 12/2023 - 06/2014
13	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 05/2007
13	CollagenIBA 01/2023 - 09/2009
11	RNA (Ribonucleic Acid)IBA 11/2023 - 01/2016
11	Choline (Choline Chloride)IBA 01/2023 - 01/2014
11	Interleukin-6 (Interleukin 6)IBA 01/2021 - 07/2003
10	InterferonsIBA 04/2023 - 10/2004
10	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2023 - 11/2010
9	cenicrivirocIBA 04/2023 - 01/2018
9	LipidsIBA 01/2023 - 10/2016
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 06/2006
8	OsteopontinIBA 09/2023 - 01/2015
8	Immune Checkpoint InhibitorsIBA 03/2021 - 06/2020
8	AdipokinesIBA 12/2019 - 05/2007
8	Methionine (L-Methionine)FDA Link 01/2019 - 01/2014
7	C-Reactive ProteinIBA 02/2024 - 06/2006
7	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 11/2023 - 02/2011
7	Hepatitis B Surface Antigens (HBsAg)FDA Link 06/2023 - 04/2007
7	Triglycerides (Triacylglycerol)IBA 01/2023 - 03/2012
7	Messenger RNA (mRNA)IBA 01/2023 - 06/2002
7	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2022 - 12/2014
7	AdiponectinIBA 12/2019 - 05/2005
6	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2024 - 01/2012
6	Insulin (Novolin)FDA Link 12/2023 - 04/2003
6	Bile Acids and Salts (Bile Acids)IBA 10/2022 - 01/2018
6	CC ChemokinesIBA 01/2022 - 08/2007
6	Peptides (Polypeptides)IBA 01/2020 - 04/2012
6	ResistinIBA 12/2019 - 06/2006
5	Liposomes (Liposome)IBA 11/2023 - 08/2014
5	Ethanol (Ethyl Alcohol)IBA 11/2023 - 10/2013
5	Amino Acids FDA Link 01/2023 - 05/2020
5	AntigensIBA 01/2023 - 01/2014
5	Fatty Acids (Saturated Fatty Acids)IBA 11/2022 - 04/2020
5	AntibodiesIBA 01/2022 - 01/2017
5	Tumor Biomarkers (Tumor Markers)IBA 10/2021 - 05/2011
5	IntegrinsIBA 08/2021 - 12/2014
5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 08/2006
4	Glucagon-Like Peptide 1 (GLP 1)IBA 03/2024 - 10/2014
4	ProcalcitoninIBA 02/2024 - 01/2009
4	InterleukinsIBA 01/2024 - 07/2011
4	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 12/2023 - 03/2012
4	Glucagon (Glukagon)FDA Link 09/2023 - 10/2014

Therapy/Procedure

87	Therapeutics 05/2024 - 10/2004
31	Liver Transplantation 02/2024 - 03/2006
12	Ligation 10/2021 - 05/2005
11	Critical Care (Surgical Intensive Care) 12/2023 - 01/2009
8	Immunotherapy 06/2024 - 10/2017
8	Transplantation 01/2023 - 02/2010
5	Drug Therapy (Chemotherapy) 07/2023 - 03/2018
4	Transjugular Intrahepatic Portasystemic Shunt 05/2024 - 02/2015
4	Surgical Portasystemic Shunt (Portosystemic Shunt) 05/2024 - 02/2015